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EMP 192
Exam 2 Review
  • Part 2
2
Question
  • Name all secretions made by the anatomical barrier that attack bacteria.
3
Answer
  • Fatty and Lactic Acid
  • Sweat
  • Tears
  • Saliva
4
Question
  • What are the bodies 3 lines of defense against pathogens?


5
Answer
  • Anatomical
  • Inflammatory
  • Immune
6
Question
  • How can you classify each line of defense?
7
Answer
  • Anatomical
    • External and Non-specific


  • Inflammatory
    • Internal and Non-specific


  • Immune
    • Internal and Specific
8
Question
  • What does each cell carry on it surface as its specific marker?
      • Hint – HLA
9
Answer
  • Anitgen
10
Question
  • State the main difference between Passive and Active Acquired Immunity.
11
Answer
  • Active Acquired Immunity
    • The individuals body develops the immunity after exposure to a specific antigen.


  • Passive Acquired Immunity
    • Transferred to the individual from an outside source.
        • Example – mother to baby.  baby didn’t develop the antibodies, mom did and passed them to baby.
12
Question
  • What is the main difference between and T lymphocyte and a B lymphocyte?
13
Answer
  • T lymphocytes
    • Directly attack the pathogen


  • B lymphocytes
    • Develop and antibody or memory cell to attack a specific
14
Question
  • What is humoral immunity?
15
Answer
  • The development of a memory cell, B lymphocyte, to develop a long-term immunity to a specific antigen.
16
Question
  • Explain the difference between and immunogen and an immunoglobulin.
17
Answer
  • Immunogen – an antigen that is able to trigger an immune response


  • Immunoglobulin – antibodies; proteins, produced in response to foreign antigens
18
Question
  • When talking about HLA and tissue transplants.  Who in the immediate family what be most reliable with a match.
    • Mother
    • Father
    • Paternal Twin
    • Identical Twin
19
Answer
  • Identical Twins


    • They com from the same fertilized egg.  Thus sharing the identical DNA.  Same DNA creates the same HLA.
20
Question
  • Where do lymphocytes come from?
21
Answer
  • All cell originate from stem cells.


    • T lymphocytes mature in the thymus
    • B lymphocytes mature in the lymphatic tissue outside the thymus
22
Question
  • The cell created by mature B lymphocytes that will create a swifter and stronger immune response when encountering an antigen for the second time.
23
Answer
  • Memory cell
24
Question
  • What are direct and indirect functions of antibodies on antigens?


25
Answer
  • Agglutination
  • Precipitation
  • Neutralization
  • Enhancement of Phagocytosis
  • Activation of plasma proteins
26
Question
  • Through the direct and indirect effects of antibodies on antigens what are the four main functions
27
Answer
  • Neutralization of Bacterial toxins
  • Neutralization of Viruses
  • Opsonization of Bacteria
  • Activation of Inflammatory processes
28
Question
  • In the first phagocyte to reach the inflamed site and ingest bacteria.
29
Answer
  • Neutrophils
    • They are mature cells that can readily ingest bacteria


      • Please remember that macrophages will do the same thing but first must mature from a monocyte. Thus slower reaction.
30
Question
  • What is a basophil?
31
Answer
  • This cell (leukocyte) reacts within the blood volume the same way a mast cell works within the tissue.  Basophils will release histamine to control vessel size.
32
Statement
  • Understand Resolution and Repair


    • Vol. 1 page 251
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Statement
  • Spend some time studying the areas in which each question comes from.  Have a working knowledge of the aspect of inflammation and immunity and you should do fine.